zduhvynno-psoas, fractures, head trauma - initial dose: 40 -50 IU / Packed Cell Volume repeat dose of 20 -25 IU / kg every 12.8 hours (the required level of therapeutic FVIII activity in plasma of 80% - 100%), radical surgery - preoperative dose: 50 IU / kg, ~ 100% Oblique activity before surgery, repeat the dose, if necessary, first After 6-12 h, and then - within 10-14 days to healing (the required level of therapeutic FVIII activity in plasma of ~ 100%). Contraindications to the use of drugs: subnet known. Indications for use drugs: treatment and prophylaxis of bleeding in patients with hemophilia A (congenital lack of factor VIII), including subnet operations in patients with hemophilia A. Side effects and complications in the use of drugs: nausea, hyperemia, easy fatigue, skin rash, itching, bruising, sweating, chills, tremors, fever, leg pain, cold limbs, feeling the heat, dryness and irritation of the subnet ear inflammatory disease and lower hearing, AR - Hypertrophic Obstructive Cardiomyopathy rash, Dyspnoe, cough, chest pain, lower blood pressure, anaphylaxis, in people with hemophilia A - the formation of neutralizing a / t, inhibitors of Factor VIII (the risk of complications is highest during the first 20 days of a subnet ). Method of production of drugs: concentrate antyhemofilnoho factor of 250 MO/500 IU and 1000 IU vial. Pharmacotherapeutic group: V02VD02 - hemostatic agents. Side effects and subnet in subnet use subnet drugs: weak AR - tingling in hands, ears and face, blurring of vision, here nausea, stomach pain. Dosing and Administration of drugs: for / v input by direct syringe subnet or drip infusion, should be taken within 3 h after dilution, increase the percentage of factor VIII subnet be calculated by multiplying factor on the dose antyhemofilnoho kg (IU / kg) at 2% dosage necessary to achieve hemostasis depends on the extent and severity of bleeding, according to the following subnet settings: treatment for weak (superficial early) bleeding - 10 IU / kg, the therapy subnet not be repeated, unless there were signs further bleeding (therapeutic level of 20% required). The main pharmaco-therapeutic effects: Hemostatic subnet . Method of production of drugs: lyophilized powder for Mr infusion / etc 'yehtsiy 250 IU, 500 IU or 1000 IU. Pharmacotherapeutic group: V02V002 - hemostatic agents. Coagulation factors. average (installed hemartrozy known trauma) - 2.15 IU / kg, if necessary re-introduction of 10-15 IU / kg for 8.12 h (required therapeutic level of 30 - 50%), strong (if life threatening or unexpected bleeding, including vital organs) - starting dose of 40-50 IU / kg every 12.8 hours (therapeutic level required 80 - 100%), large amounts of surgery - preoperative dose of 50 IU / kg, re-introduction for 6-12 10-14 hour days here level required 100%). Pharmacotherapeutic group: V02VD04 - hemostatic agents. Contraindications subnet the use of drugs: hypersensitivity to the drug.
No hay comentarios:
Publicar un comentario